Latest Bioinformatics News
PRIMe: a method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studiesMotivation: The concept of pleiotropy was proposed a century ago, though up to now there have been insufficient efforts to design robust statistics and software aimed at visualizing and evaluating pleiotropy at a regional level. The Pleiotropic Region Identification Method (PRIMe) was developed to evaluate potentially pleiotropic loci based upon data...
aCGH.Spline–an R package for aCGH dye bias normalizationMotivation: The careful normalization of array-based comparative genomic hybridization (aCGH) data is of critical importance for the accurate detection of copy number changes. The difference in labelling affinity between the two fluorophores used in aCGH—usually Cy5 and Cy3—can be observed as a bias within the intensity distributions. If...
Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis softwareSummary: There is a strong and growing need in the biology research community for accurate, automated image analysis. Here, we describe CellProfiler 2.0, which has been engineered to meet the needs of its growing user base. It is more robust and user friendly, with new algorithms and features to facilitate high-throughput work. ImageJ plugins can now...
BiC: a web server for calculating bimodality of coexpression between gene and protein networksSummary: Bimodal patterns of expression have recently been shown to be useful not only in prioritizing genes that distinguish phenotypes, but also in prioritizing network models that correlate with proteomic evidence. In particular, subgroups of strongly coexpressed gene pairs result in an increased variance of the correlation distribution. This variance,...
SiGN-SSM: open source parallel software for estimating gene networks with state space modelsSummary: SiGN-SSM is an open-source gene network estimation software able to run in parallel on PCs and massively parallel supercomputers. The software estimates a state space model (SSM), that is a statistical dynamic model suitable for analyzing short time and/or replicated time series gene expression profiles. SiGN-SSM implements a novel parameter...
STOCHSIMGPU: parallel stochastic simulation for the Systems Biology Toolbox 2 for MATLABMotivation: The importance of stochasticity in biological systems is becoming increasingly recognized and the computational cost of biologically realistic stochastic simulations urgently requires development of efficient software. We present a new software tool STOCHSIMGPU that exploits graphics processing units (GPUs) for parallel stochastic simulations...
Bioinformatics Jobs
Bioinformatics Introductory Statistics with R(Statistics and Computing)Bioinformatics Introductory Statistics with R (Statistics and Computing) R is an Open Source implementation...
AMSTAT – Scientist – Bioinformatics at Genentech (South San Francisco, CA)in our South San Francisco, CA, headquarters: Scientist – Bioinformatics Responsibilities: Genentech...
Bioinformatics/Software Engineer at Sapphire (Cambridge, MA)Sapphire Technologies, a Randstad company, is one of US’ premier IT staffing firms. Locally voted...
Bioinformatics Analyst at Georgetown University (Washington, DC)Number: 2010-0425D Job Title: Bioinformatics Analyst Department: LOMBARDI DRUG DISCOVERY & DEVELOPMENTAL...
Bioinformatics Systems Engineer I – Center for Human Genetics – Vanderbilt University – Nashville, TNThe Vanderbilt University Center for Human Genetics research is seeking an entry-level software developer...
Genoinformatics News
Mitrionics Announces Hybrid Computing Development System Based on SGI Altix XE 320 Quad-Core, Dual-Socket Server With Low Latency Front Side Bus (FSB) InterfaceMitrionics, Inc., developer of the Mitrion™ Virtual Processor and the Mitrion Software Acceleration Platform, today announced its Mitrionics MVP622 Hybrid Computing Server accelerated computing...
Cited for two of the ‘best conferences’ in genome biology, CSHL gears up for 2nd annual Personal Genomes meetingFor decades, scientific meetings at Cold Spring Harbor Laboratory ( CSHL ) have been held in great esteem by scientists for their role in shaping the agenda of molecular biology. Their reputation...
Chemoinformatics News
NOESIS TO BUILD UPON OPENEYE’S CHEMINFORMATICS TOOLKIT OECHEMOpenEye Scientific Software, Inc., the developer of innovative molecular modeling and cheminformatics solutions for drug discovery research, and Noesis ChemoInformatics Ltd, a new developer of lead...
GVK Biosciences (GVK BIO) along with Wyeth Research won the prestigious European Outsourcing Award 2009GVK Biosciences (GVK BIO) along with Wyeth Research won the prestigious European Outsourcing Award 2009 for the Best New Partnership. The award was received by Manni Kantipudi, President, GVK BIO at...


